those error messages might be "vague" to you but they have meanings so it would be helpful to know what they are

Download the nightly builds: https://developer.joomla.org/nightly-builds.html

those error messages might be "vague" to you but they have meanings so it would be helpful to know what they are

My bad! Here's a step by step with error messages:

In php.ini:
upload_max_filesize = 50M

1. From home dashboard in Joomla 4.0.0-alpha-12 I click Joomla Update.

2. Click Upload & Update tab.

3. It says:
   Joomla package file
Maximum upload size: ‎20.00 MB

4. Click Browse.

5. Select Joomla_4.0.0-beta1-Beta-Update_Package.zip (24 MB)

6. Click Upload & Install.

7. Error (admin site error popup)

COM_INSTALLER_MSG_INSTALL_WARNINSTALLUPLOADERROR
COM_INSTALLER_MSG_WARNINGS_SMALLUPLOADSIZE

In the page error message:

An error has occurred.

403 Access forbidden.

(Return to Dashboard) button.

Download the nightly builds: https://developer.joomla.org/nightly-builds.html

Thanks. Is there a git command to install these over the top of an existing 4.0.0-alpha12 instance?

Suggestion, it'd be nice for the Joomla Updater to be able to git or wget these nightly builds and upgrade packages on the joomla server, directly from github, and from the joomla.org nightly builds site, and thereby get around the PHP client browser upload_max_filesize limit!

Use custom update server: https://update.joomla.org/core/nightlies/next_major_list.xml

I've fixed the issue with uploading. It was caused by PHP reading values in from the global php.ini not the local file, as soon as I edited the global php.ini file setting upload_max_filesize to 50M then the upload worked, and it upgraded.

However, there is still an error, with no clear way to resolve it from inside the admin site:

Warning

There are tables not up to date!
Joomla! 4 Content Management System.
One Problem

    The Joomla! Core database tables have not been converted yet to UTF-8 Multibyte (utf8mb4).
    159 database changes were checked.
    252 database changes did not alter table structure and were skipped.

	4.0.0-2020-05-29 	‎4.0.0-beta1 	N/A 	205

How to resolve this error? Shouldn't Joomla issue the commands to MySQL to convert all to utf8mb4? Does it expect the admin to run a command line command? It's not a very clear/simple user experience here!

It's not a very clear/simple user experience here!

The Joomla Project has never officially supported Alpha to Beta upgrades and doesn't cater for "users" at this stage of development.

How to resolve this error? Shouldn't Joomla issue the commands to MySQL to convert all to utf8mb4?

Login to Admin -> System -> Database -> Select Joomla CMS -> Click Update Structure

The Joomla Project has never officially supported Alpha to Beta upgrades and doesn't cater for "users" at this stage of development.

Exactly. Details can be found in the following discussion in the Joomla Support Forum: https://forum.joomla.org/viewtopic.php?p=3607365&sid=e2cbc571de4b7fafa4f9b6befa948ea5#p3606084.

It's not a very clear/simple user experience here!

The Joomla Project has never officially supported Alpha to Beta upgrades and doesn't cater for "users" at this stage of development.

I meant to say, the UX for the admin site is not clear here in terms of the error message is overly vague as it fails to say how to resolve this charset issue in a way that won't break this joomla instance. Since it's just commands to the database, that will change the charsets, why on earth doesn't it just contain the commands in the code and fix the problem for us rather than leave it up to a human?

How to resolve this error? Shouldn't Joomla issue the commands to MySQL to convert all to utf8mb4?

Login to Admin -> System -> Database -> Select Joomla CMS -> Click Update Structure

I did this already, and yet, it continues to complain with the same exact error, as if it didn't actually change the charsets of all tables, columns and rows (?).
After clicking Update structure, it still says:

Warning

There are tables not up to date!

As @richard67 explained, it is not an issue.

Isn't the standard Joomla way of upgrading from one version to the next, the new version, in this case 4.0 Beta, is supposed to come with a SQL file to upgrade the database of 4.0 Alpha so that it'll be in the schema expected by the code of 4.0 Beta?

@chris001 Between alpha and beta we had to change the existing 4.0 schema update SQL files a few times and these will not run again if your database schema version is already higher. We had to do that because otherwise we would have some 500 4.0 update sql scripts now. So please accept what I and others say who have done these work and know the database well enough to know what they are talking about, ok?

I say again:

The Joomla Project has never officially supported Alpha to Beta upgrades and doesn't cater for "users" at this stage of development.